Product Description: DNase I (EC 3.1.21.1) is an enzyme that degrade DNA, it plays a key role in the cleavage of extracellular DNA is crucial for limiting the inflammatory response and maintaining homeostasis. Exogenous deoxyribonuclease shows beneficial effects in inflammatory diseases and cancer[1].
Applications: COVID-19-immunoregulation
Formula: N/A
References: [1]Lauková L, et al. Deoxyribonucleases and Their Applications in Biomedicine. Biomolecules. 2020 Jul 11;10(7):1036./[2]Sugihara S, et al. Deoxyribonuclease treatment prevents blood-borne liver metastasis of cutaneously transplanted tumour cells in mice. Br J Cancer. 1993 Jan;67(1):66-70.
CAS Number: 9003-98-9
Molecular Weight: N/A
Research Area: Cancer; Inflammation/Immunology
Solubility: DMSO : 43.48 mg/mL (adjust pH to 3 with 1M HCl)/H2O : < 0.1 mg/mL (ultrasonic;warming;heat to 60°C)