PAF Acetylhydrolase (human, recombinant)

Formulation: 50 mM sodium phosphate, pH 7.2, 100 mM NaCl, 10% glycerol

Purity: ≥80% estimated by SDS-PAGE

Shelf life (days): 730

Notes: Platelet-activating factor (PAF) is an important lipid mediator involved in inflammation. PAF-acetylhydrolase (PAF-AH) is an extracellular phospholipase A2 which hydrolyzes the acetyl group at the sn-2 position of phospholipids.{2618} Two main types of PAF-AH have been characterized, namely the secreted (i.e. plasma) and intracellular enzymes, which are encoded on individual genes and share only 41% homology at the amino acid level.{4758,6501} Cayman’s PAF-AH is the secreted calcium-independent isoform. PAF deacetylation by PAF-AH causes loss of biological activity, making PAF-AH potentially useful as an anti-inflammation therapy.

• Artikelnummer: CAY10279
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 10279-100
• Green Labware: Nein
• Verpackungseinheit: 100 µg
• Mengeneinheit: STK