Product Description: Ac-ANW-AMC is a fluorogenic substrate for immunoproteasome. Ac-ANW-AMC can be used to measure β5i activity (Ex=345 nm, Em=445 nm)[1][2].
Formula: C30H32N6O7
References: [1]Winter, M.B., La Greca, F., Arastu-Kapur, S., et al. Immunoproteasome functions explained by divergence in cleavage specificity and regulation. eLife 6:e27364, (2017). /[2]Sumin Kim, et al. Evaluation of Immunoproteasome-Specific Proteolytic Activity Using Fluorogenic Peptide Substrates. Immune Netw. 2022 Apr 15;22(3):e28.
CAS Number: 2357123-49-8
Molecular Weight: 588.61
Research Area: Inflammation/Immunology
Solubility: 10 mM in DMSO
Target: Proteasome