BODIPY FL prazosin, CAS 175799-93-6

Product Description: BODIPY FL prazosin is a fluorescent α1-adrenergic antagonist with Ki values of 14.5, 43.3 nM for α1a-AR and α1b-AR, respectively. BODIPY FL prazosin also is a fluorescent ligand with the excitation and emission wavelengths are 485 and 535 nm, respectively. BODIPY FL prazosin can be used for study the differences in the subcellular localization of α1-adrenoceptor subtypes[1][2][3].

Formula: C28H32BF2N7O3

References: [1]Sugawara T, et al. Differences in the subcellular localization of alpha1-adrenoceptor subtypes can affect the subtype selectivity of drugs in a study with the fluorescent ligand BODIPY FL-prazosin. Life Sci. 2002 Mar 22;70(18):2113-24./[2]Cerveny L, et al. Lack of interactions between breast cancer resistance protein (bcrp/abcg2) and selected antiepileptic agents. Epilepsia. 2006 Mar;47(3):461-8./[3]Fuchs R, et al. α1-adrenergic drugs exhibit affinity to a thapsigargin-sensitive binding site and interfere with the intracellular Ca2+ homeostasis in human erythroleukemia cells. Exp Cell Res. 2011 Dec 10;317(20):2969-80.

CAS Number: 175799-93-6

Molecular Weight: 563.41

Research Area: Metabolic Disease

Solubility: 10 mM in DMSO

Target: Adrenergic Receptor

• Artikelnummer: MEXHY-D1606-0
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-D1606-0
• Green Labware: Nein
• Verpackungseinheit: Get quote
• Mengeneinheit: STK