EDTA-AM, CAS 162303-59-5

Product Description: EDTA-AM (ethylenediaminetetraacetic acid, acetoxymethyl ester) is the membrane-permeant form of the metal chelator EDTA (HY-Y0682). Live cells passively load EDTA-AM by incubating with EDTA-AM. Once internalized, cytoplasmic esterase decomposes AM esters, releasing the active ligand EDTA, which isolates metal ions within the cell. EDTA-AM induces an arrest of mitotic progression and chromosome decondensation[1][2].

Formula: C22H32N2O16

References: [1]Watkins CS, et.al. Effects on K+ currents in rat cerebellar granule neurones of a membrane-permeable analogue of the calcium chelator BAPTA. Br J Pharmacol. 1996 Aug;118(7):1772-8. /[2]Maeshima K, et.al. A Transient Rise in Free Mg2+Ions Released from ATP-Mg Hydrolysis Contributes to Mitotic Chromosome Condensation. Curr Biol. 2018 Feb 5;28(3):444-451.e6.

CAS Number: 162303-59-5

Molecular Weight: 580.49

Compound Purity: 98.0

Research Area: Others

Solubility: DMSO : 100 mg/mL (ultrasonic)

Target: Biochemical Assay Reagents

• Artikelnummer: MEXHY-D1746-25
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-D1746-25
• Green Labware: Nein
• Verpackungseinheit: 25 mg
• Mengeneinheit: STK