Product Description: FSB is a fluorescent dye that can be used to detect filamentous tau and to label human amyloid lesions with high sensitivity and specificity (excitation: 390 nm, emission: 520 nm)[1][2].
Applications: Neuroscience-Neurodegeneration
Formula: C24H17FO6
References: [1]Velasco A, et al. Detection of filamentous tau inclusions by the fluorescent Congo red derivative FSB [(trans,trans)-1-fluoro-2,5-bis(3-hydroxycarbonyl-4-hydroxy)styrylbenzene]. FEBS Lett. 2008 Mar 19;582(6):901-6. /[2]Sato K, et al. Fluoro-substituted and 13C-labeled styrylbenzene derivatives for detecting brain amyloid plaques. Eur J Med Chem. 2004 Jul;39(7):573-8.
CAS Number: 760988-03-2
Molecular Weight: 420.39
Compound Purity: 99.5
Research Area: Neurological Disease
Solubility: DMSO : 200 mg/mL (ultrasonic;warming)
Target: Amyloid-β