Hoechst 33258 (trihydrochloride), CAS 23491-45-4

Product Description: Hoechst 33258 trihydrochloride is a marker dye in Hoechst series. Hoechst is A live nuclear marker dye. Hoechst binds to the grooves in the DNA double strand, which tends to be A/ T-rich DNA strand. Although it binds to all nucleic acids, the A/ T-rich double strand DNA significantly enhances fluorescence intensity Therefore,Hoechst dye can be used for living cell labeling. The fluorescence intensity of Hoechst dye increases with the increase of pH of solution[1].

Applications: Cancer-programmed cell death

Formula: C25H27Cl3N6O

References: [1]Wang XJ, et al. Newly synthesized bis-benzimidazole derivatives exerting anti-tumor activity through inductionof apoptosis and autophagy. Bioorg Med Chem Lett. 2012 Oct 1;22(19):6297-300./[2]Stolić I, et al. Synthesis, DNA/RNA affinity and antitumour activity of new aromatic diamidines linked by 3,4-ethylenedioxythiophene. Eur J Med Chem. 2011 Feb;46(2):743-55.

CAS Number: 23491-45-4

Molecular Weight: 533.88

Compound Purity: 99.71

Research Area: Cancer

Solubility: DMSO : 100 mg/mL (ultrasonic)/H2O : 12.5 mg/mL (ultrasonic;warming;heat to 60°C)

Target: Fluorescent Dye

• Artikelnummer: MEXHY-15558A-10.1
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-15558A-10.1
• Green Labware: Nein
• Verpackungseinheit: 10mM/1mL
• Mengeneinheit: STK