Proflavine (hemisulfate), CAS 1811-28-5

Product Description: Proflavine hemisulfate, an acridine dye, is a known DNA intercalating agent. Anti-microbial agent[1]. Proflavine hemisulfate behaves as a pore blocker for Kir3.2. Proflavine hemisulfate is a potential lead compound for Kir3.2-associated neurological diseases[2].

Applications: COVID-19-immunoregulation

Formula: C13H11N3.1/2H2SO4

References: [1]Hitoshi Kawada, et al. Isolation of proflavine as a blocker of G protein-gated inward rectifier potassium channels by a cell growth-based screening system. Neuropharmacology. 2016 Oct;109:18-28./[2]Mansour K.Gatasheh, et al. Proflavine an acridine DNA intercalating agent and strong antimicrobial possessing potential properties of carcinogen. Karbala International Journal of Modern Science. 2017 Dec, 3(4): 272-278./[3]Jiaxin Chen, et al. Determination of proflavine in rat whole blood without sample pretreatment by laser desorption postionization mass spectrometry. Anal Bioanal Chem. 2017 Apr;409(11):2813-2819.

CAS Number: 1811-28-5

Molecular Weight: 258.28

Compound Purity: 98.45

Research Area: Infection; Cancer

Solubility: H2O : ≥ 5 mg/mL

Target: Autophagy;Bacterial;Potassium Channel

• Artikelnummer: MEXHY-B0883-10.1
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-B0883-10.1
• Green Labware: Nein
• Verpackungseinheit: 10mM/1mL
• Mengeneinheit: STK