Propidium monoazide, CAS 91416-20-5

Product Description: Propidium monoazide is a photoreactive DNA-binding dye that preferentially binds to dsDNA. Propidium monoazide (PMA) prevents DNA from dead bacteria from being amplified during the PCR. PMA-PCR enhanced both the specificity and the sensitivity of PCR[1]. Propidium monoazide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. Strain-promoted alkyne-azide cycloaddition (SPAAC) can also occur with molecules containing DBCO or BCN groups.

Formula: C27H32Cl2N6

References: [1]Mohamed Askar 1, et al. Propidium monoazide-polymerase chain reaction for detection of residual periprosthetic joint infection in two-stage revision. Mol Biol Rep. 2019 Dec;46(6):6463-6470.

CAS Number: 91416-20-5

Molecular Weight: 511.49

Compound Purity: 99.0

Research Area: Infection

Solubility: 10 mM in DMSO

Target: Fluorescent Dye

• Artikelnummer: MEXHY-D1444-1
• Hersteller: MedChemExpress
• Hersteller Artikelnummer: HY-D1444-1
• Green Labware: Nein
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK