Formosanin C, CAS 50773-42-7

Formulation: A solid

Formal Name: (3β,25R)-spirost-5-en-3-yl O-6-deoxy-α-L-mannopyranosyl-(1→2)-O-[O-6-deoxy-α-L-mannopyranosyl-(1→4)-6-deoxy-α-L-mannopyranosyl-(1→4)]-β-D-glucopyranoside

Purity: ≥98%

Formula Markup: C51H82O20

Formula Weight: 1015,2

Shelf life (days): 1460

CAS Number: 50773-42-7

Notes: Formosanin C is a diosgenin saponin that has been found in P. formosana and has diverse biological activities.{67639,67640,67641,67642} It is active against C. albicans (MIC = 1 µg/ml) and inhibits C. albicans biofilm formation (MIC = 25 µg/ml).{67639} Formosanin C (0.625-5 µM) inhibits LPS-induced production of prostaglandin E2 (PGE2; Item No. 14010) and nitric oxide (NO) in RAW 264.7 macrophages.{67640} It induces lipid peroxidation and ferroptosis in MDA-MB-231 breast cancer cells when used at a concentration of 5 µM.{67641} In vivo, formosanin C (1.5 mg/kg) delays disease onset in a guinea pig model of S-antigen-induced experimental autoimmune uveitis (EAU).{67642}

• Artikelnummer: CAY40236-5
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 40236-5
• Verpackungseinheit: 5 mg
• Mengeneinheit: STK