GDC-6036, CAS 2417987-45-0

Formulation: A solid

Formal Name: 1-[(3S)-4-[(7R)-7-[6-amino-4-methyl-3-(trifluoromethyl)-2-pyridinyl]-6-chloro-8-fluoro-2-[[(2S)-1-methyl-2-pyrrolidinyl]methoxy]-4-quinazolinyl]-3-methyl-1-piperazinyl]-2-propen-1-one

Purity: ≥98%

Formula Markup: C29H32ClF4N7O2

Formula Weight: 622,1

Shelf life (days): 1460

CAS Number: 2417987-45-0

Notes: GDC-6036 is a covalent inhibitor of K-Ras containing a glycine-to-cysteine substitution at position 12 (K-RasG12C).{72536} It decreases tumor volume in a PaCa-2 pancreatic cancer mouse xenograft model when administered at doses ranging from 1 to 100 mg/kg per day.

• Artikelnummer: CAY41852-10
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 41852-10
• Verpackungseinheit: 10 mg
• Mengeneinheit: STK