Formulation: A crystalline solid
Formal Name: 7,9-dihydro-1,3,7-tri(methyl-d3)-1H-purine-2,6,8(3H)-trione
Purity: ≥99% deuterated forms (d1-d9)
Formula Markup: C8HD9N4O3
Formula Weight: 219,2
Shelf life (days): 730
CAS Number: 117490-42-3
Notes: 1,3,7-Trimethyluric acid-d9 is intended for use as an internal standard for the quantification of 1,3,7-trimethyluric acid (Item No. 16949) by GC- or LC-MS. 1,3,7-Trimethyluric acid is a derivative of uric acid (Item No. 16219) and a metabolite of caffeine (Item No. 14118).{58128} It is formed from caffeine by the cytochrome P450 (CYP) isoform CYP3A4. 1,3,7-Trimethyluric acid (500 µM) scavenges hydroxyl radicals in a cell-free assay and inhibits t-butyl hydroperoxide-induced lipid peroxidation by 56.5% in isolated human erythrocyte membranes.{58129}