1,3-Dimethyluric Acid, CAS 944-73-0

Formulation: A solid

Formal Name: 7,9-dihydro-1,3-dimethyl-1H-purine-2,6,8(3H)-trione

Purity: ≥98%

Formula Markup: C7H8N4O3

Formula Weight: 196,2

Shelf life (days): 1460

CAS Number: 944-73-0

Notes: 1,3-Dimethyluric acid is an active metabolite of the methylxanthine alkaloids caffeine (Item No. 14118) and theophylline (Item No. 23760).{57870} It is formed from caffeine and theophylline by the cytochrome P450 (CYP) isoforms CYP1A2 and CYP2E1.{68171,68169} 1,3-Dimethyluric acid (500 µM) scavenges hydroxyl radicals in a cell-free assay and inhibits t-butyl hydroperoxide-induced lipid peroxidation by 77% in isolated human erythrocyte membranes.{58129} It induces contractions in isolated rabbit duodenal, jejunal, and ileal preparations, but induces relaxation in isolated rabbit ascending colon preparations, in a concentration-dependent manner.{68170} Intracerebral administration of 1,3-dimethyluric acid induces clonic convulsions in mice (ED50 = 360 nmol/animal).{60652} It has been found in urinary caliculi.{33336}

• Artikelnummer: CAY36167-250
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 36167-250
• Green Labware: Nein
• Verpackungseinheit: 250 mg
• Mengeneinheit: STK
• Methode: Reinstoffe