1-Arachidonoyl Glycerol, CAS 35474-99-8

Formulation: A solution in acetonitrile

Formal Name: 5Z,8Z,11Z,14Z-eicosatetraenoic acid, 1-glyceryl ester

Purity: ≥95% (as a 9:1 mixture of the 1-AG and 2-AG)

Formula Markup: C23H38O4

Formula Weight: 378,6

Shelf life (days): 365

CAS Number: 35474-99-8

Notes: The glyceryl esters of arachidonic acid have been proposed as endogenous cannabinoid ligands.{4614} 2-AG is 10 to 100 times more potent than 1-AG in ligand binding affinity and agonist activity at the CB1 receptor, and is thus considered to be the natural ligand.{5306} However, 2-AG is chemically unstable and undergoes rapid isomerization to 1-AG (synonymous with 1(3)-AG) both in vitro and in vivo. 1-AG is a frequent contaminant in synthetic 2-AG preparations, and can markedly reduce their cannabinergic potency. 1-AG is a weak CB1 receptor agonist and may have other pharmacologic properties.

• Artikelnummer: CAY62150-1
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 62150-1
• Green Labware: Nein
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK