1-Linoleoyl-2-hydroxy-sn-glycero-3-PA (sodium salt), CAS 72777-86-7

Formulation: A solid

Formal Name: 9Z,12Z-octadecadienoic acid, 2R-hydroxy-3-(phosphonooxy)propyl ester, sodium salt

Purity: ≥95% (mixture of isomers)

Formula Markup: C21H39O7P • XNa

Formula Weight: 434,5

Shelf life (days): 1460

CAS Number: 72777-86-7

Notes: 1-Linoleoyl-2-hydroxy-sn-glycero-3-PA (sodium salt) (1-linoleoyl LPA) is an agonist of the LPA2 receptor and a glycerophospholipid containing linoleic acid (Item Nos. 90150 / 90150.1 / 21909) at the sn-1 position.{43503} It is the most abundant LPA in mouse and human plasma.{66452,66453} 1-Linoleoyl LPA selectively increases intracellular calcium levels in LPA2 receptor-expressing Sf9 cells (EC50 = ~10 nM) over LPA1 and LPA3 receptor-expressing Sf9 cells (EC50s = ~200 and ~80 nM, respectively).{43503} Serum levels of 1-linoleoyl LPA are increased in mice bearing NCTC clone 2472 tumors.{66454} Plasma 1-linoleoyl LPA levels are decreased in patients with primary progressive, but not relapsing-remitting, multiple sclerosis and are negatively correlated with neurological deficit severity.{66455}

• Artikelnummer: CAY38309-500
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 38309-500
• Green Labware: Nein
• Verpackungseinheit: 500 µg
• Mengeneinheit: STK