2-Phenylaminoadenosine, CAS 53296-10-9

2-Phenylaminoadenosine, CAS 53296-10-9
Artikelnummer
CAY28734-25
Verpackungseinheit
25 mg
Hersteller
Cayman Chemical

Verfügbarkeit: wird geladen...
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Formulation: A solid

Purity: ≥98%

Formula Markup: C16H18N6O4

Formula Weight: 358,4

Shelf life (days): 1460

CAS Number: 53296-10-9

Notes: 2-Phenylaminoadenosine is an adenosine receptor agonist.{48560} It binds to adenosine A1 receptors in rat cortical membranes (IC50 = 910 nM) and A2 receptors in rat striatal membranes (IC50 = 115 nM). 2-Phenylaminoadenosine increases coronary flow in a perfused working rat heart model ex vivo (EC25 = 110 nM). It decreases blood pressure in normotensive (ED25 = 28 μg/kg) and spontaneously hypertensive rats (SHR; ED30 = 5.32 μg/kg).{48560,48561} 2-Phenylaminoadenosine (500 nmol/kg) increases L-dihydroxyphenylalanine (L-DOPA; Item No. 13248) accumulation in rat striatum.{48562} It also inhibits conditioned avoidance responding (CAR) to electric shock in rats (ED50 = 1.3 mg/kg).{48563}
Mehr Informationen
Artikelnummer CAY28734-25
Hersteller Cayman Chemical
Hersteller Artikelnummer 28734-25
Green Labware Nein
Verpackungseinheit 25 mg
Mengeneinheit STK
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