3,4-Dihydroxymandelic Acid, CAS 775-01-9

Formulation: A solid

Formal Name: α,3,4-trihydroxy-benzeneacetic acid

Purity: ≥95%

Formula Markup: C8H8O5

Formula Weight: 184,1

Shelf life (days): 1460

CAS Number: 775-01-9

Notes: 3,4-Dihydroxymandelic acid is an active metabolite of the endogenous catecholamine (–)-norepinephrine (Item No. 16673).{66349} It is formed from (–)-norepinephrine via the intermediate norepinephrine aldehyde by aldehyde dehydrogenase. 3,4-Dihydroxymandelic acid scavenges superoxide radicals (IC50 = 130 nM) and reduces lipid peroxidation in cell-free assays.{66350} 3,4-Dihydroxymandelic acid is also formed from norepinephrine by gut microbiota, such as E. coli.{66351} It is a chemoattractant for enterohemorrhagic E. coli that induces the expression of virulence genes when used at a concentration of 50 µM and increases the attachment of enterohemorrhagic E. coli to HeLa cells in vitro.

• Artikelnummer: CAY36369-50
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 36369-50
• Green Labware: Nein
• Verpackungseinheit: 50 mg
• Mengeneinheit: STK
• Methode: Reinstoffe