3-Aminopropylphosphonic Acid, CAS 13138-33-5

Formulation: A crystalline solid

Formal Name: P-(3-aminopropyl)-phosphonic acid

Purity: ≥95%

Formula Markup: C3H10NO3P

Formula Weight: 139,1

Shelf life (days): 1460

CAS Number: 13138-33-5

Notes: 3-Aminopropylphosphonic acid (3-APPA) is a phosphonic analog of GABA that acts as a partial agonist of GABAB receptors (IC50 = 1.5 μM in a radioligand binding assay).{36477,23832} It induces relaxation in unstimulated isolated guinea pig ileum longitudinal muscle and reverses GABA- and baclofen-induced inhibition of twitch responses in isolated guinea pig ileum longitudinal muscle.{36477} 3-APPA (5 mg/kg) completely inhibits GABA- and baclofen-induced inhibition of vagally stimulated bronchospasms in guinea pigs.{36478} It also reverses the antitussive effect of baclofen in cats when administered at a dose of 3 mg/kg.{36479}

• Artikelnummer: CAY23556-250
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 23556-250
• Green Labware: Nein
• Verpackungseinheit: 250 mg
• Mengeneinheit: STK