3-Methylxanthine, CAS 1076-22-8

Formulation: A solid

Formal Name: 3,9-dihydro-3-methyl-1H-purine-2,6-dione

Purity: ≥98%

Formula Markup: C6H6N4O2

Formula Weight: 166,1

Shelf life (days): 1460

CAS Number: 1076-22-8

Notes: 3-Methylxanthine is a cGMP phosphodiesterase (PDE) inhibitor and a metabolite of theophylline (Item No. 23760) and caffeine (Item No. 14118).{60649,60650,60651} It is formed from theophylline by the cytochrome P450 (CYP) isoform CYP1A2 and from caffeine via 6A5NF-1,3-dimethyluracil, 1,3,7-trimethyluric acid, or theobromine intermediates. 3-Methylxanthine inhibits cGMP PDE in isolated guinea pig trachealis muscle with an IC50 value of 920 µM.{60649} It is neurotoxic to mice, inducing convulsions with an ED50 value of 1,107 nmol/kg.{60652}

• Artikelnummer: CAY34288-5
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 34288-5
• Green Labware: Nein
• Verpackungseinheit: 5 g
• Mengeneinheit: STK