(±)5(6)-DiHET, CAS 213382-49-1

Formulation: A solution in ethanol

Formal Name: (±)5,6-dihydroxy-8Z,11Z,14Z-eicosatrienoic acid

Purity: ≥95%

Formula Markup: C20H34O4

Formula Weight: 338,5

Shelf life (days): 365

CAS Number: 213382-49-1

Notes: 5(6)-DiHET is a fully racemic version of the enantiomeric forms biosynthesized from 5(6)-EET (Item Nos. 50211 / 10007260) by epoxide hydrolases.{729} 5(6)-DiHET can be used to quantify 5(6)-EET due to the conversion of 5(6)-EET to 5(6)-δ-lactone in solution.{39654} 5(6)-DiHET activates large-conductance calcium-activated potassium (KCa1.1/BK) channels in smooth muscle cells from rat small coronary arteries.{37444} It is a substrate for sheep seminal vesicle COX, producing 5,6-dihydroxy prostaglandin E1 and F1α metabolites in vitro.{461} 5(6)-DiHET levels decrease in plasma in a high-fat diet-induced rat model of hyperlipidemia.{37445}

• Artikelnummer: CAY51211-100
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 51211-100
• Green Labware: Nein
• Verpackungseinheit: 100 µg
• Mengeneinheit: STK