AB-928, CAS 2239273-34-6

Formulation: A crystalline solid

Formal Name: 3-[2-amino-6-[1-[[6-(1-hydroxy-1-methylethyl)-2-pyridinyl]methyl]-1H-1,2,3-triazol-4-yl]-4-pyrimidinyl]-2-methyl-benzonitrile

Purity: ≥98%

Formula Markup: C23H22N8O

Formula Weight: 426,5

Shelf life (days): 1460

CAS Number: 2239273-34-6

Notes: AB-928 is an adenosine A2A and A2B receptor dual antagonist.{58116} It inhibits the ability of adenosine (Item No. 21232) to suppress activation of human CD4 or CD8 T cells, as well as monocyte-derived dendritic cells, in vitro.{58117,58118} AB-928, alone or in combination with doxorubicin (Item No. 15007), reduces tumor growth in an AT3-OVA syngeneic mouse model. It also acts synergistically with an anti-PD-1 antibody to reduce tumor growth in a B16/F10 syngeneic mouse model.

• Artikelnummer: CAY31444-10
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 31444-10
• Green Labware: Nein
• Verpackungseinheit: 10 mg
• Mengeneinheit: STK