Acetyl β-Endorphin (human) (trifluoroacetate salt)

Formulation: A lyophilized powder

Purity: ≥95%

Formula Markup: C160H253N39O47S • XCF3COOH

Formula Weight: 3507

Shelf life (days): 1460

Notes: Acetyl β-endorphin is an acetylated derivative of β-endorphin that binds to opioid receptors in rat caudal dorsomedial medulla (Ki = 490 nM) and mouse brain membrane preparations (IC50 = 109 nM).{40897,40895} It induces chemotaxis of human monocytes in vitro when used at a concentration of 0.1 nM.{40896} In vivo, it reduces antinociception in mice induced by β-endorphin (Item Nos. 24153 / 24955), morphine, [D-Ala2, N-Me-Phe4, Gly5-ol]-enkephalin (DAMGO; Item No. 21553), and [D-Ala2, D-Leu5]-enkephalin (DADLE) in a tail-flick test (ED50s = 2.08, 33.11, 0.03, and 0.07 mol per animal, respectively).{40895}

• Artikelnummer: CAY24953
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 24953-1
• Green Labware: Nein
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK