Acetyl PACAP (1-38) (human, mouse, ovine, porcine, rat) (trifluoroacetate salt)

Formulation: A lyophilized powder

Formal Name: N-acetyl-L-histidyl-L-seryl-L-α-aspartylglycyl-L-isoleucyl-L-phenylalanyl-L-threonyl-L-α-aspartyl-L-seryl-L-tyrosyl-L-seryl-L-arginyl-L-tyrosyl-L-arginyl-L-lysyl-L-glutaminyl-L-methionyl-L-alanyl-L-valyl-L-lysyl-L-lysyl-L-tyrosyl-L-leucyl-L-alanyl-L-alanyl-L-valyl-L-leucylglycyl-L-lysyl-L-arginyl-L-tyrosyl-L-lysyl-L-glutaminyl-L-arginyl-L-valyl-L-lysyl-L-asparaginyl-L-lysinamide, trifluoroacetate salt

Purity: ≥95%

Formula Markup: C205H333N63O54S • XCF3COOH

Formula Weight: 4576,3

Shelf life (days): 1460

Notes: Acetyl pituitary adenylate cyclase-activating peptide (PACAP) (1-38) is an N-terminally acetylated form of PACAP (1-38) (Item No. 24770).{41742} It binds to the PACAP receptor PAC1 (IC50 = 5.6 nM for the human receptor) and induces calcium mobilization and proliferation of PC12 cells (EC50s = 4.4 and 0.83 nM, respectively) with an efficacy comparable to PACAP (1-38). Acetyl PACAP (1-38) is resistant to degradation by dipeptidyl peptidase 4 (DPP-4) with a 10-fold longer half-life than PACAP (1-38), respectively.

• Artikelnummer: CAY24774
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 24774-500
• Green Labware: Nein
• Verpackungseinheit: 500 µg
• Mengeneinheit: STK