Formulation: A solid
Formal Name: 2-(acetylthio)-N,N,N-trimethyl-ethanaminium, monoiodide
Purity: ≥95%
Formula Markup: C7H16NOS • I
Formula Weight: 289,2
Shelf life (days): 1460
CAS Number: 1866-15-5
Notes: Acetylthiocholine is a substrate for acetylcholinesterase (AChE) and an agonist of α4β2 subunit-containing nicotinic acetylcholine receptors (nAChRs).{60571,27173} It binds to α4β2 subunit-containing nAChRs in SH-EP1 cells (IC50 = 7.1 µM for the human receptor) and induces rubidium efflux in an agonist-induced rubidium efflux assay (EC50 = 100 µM).{27173} Acetylthiocholine has been used as part of a thiocholine sensor for the detection of pesticides in complex sample types, such as soil, groundwater, and spinach.{60571}