ACTH (1-13) (human, mouse, rat, porcine, bovine, ovine) (trifluoroacetate salt)

Formulation: A solid

Formal Name: α1-13-corticotropin, trifluoroacetate salt

Purity: ≥98%

Formula Markup: C75H106N20O19S • XCF3COOH

Formula Weight: 1623,8

Shelf life (days): 1460

Notes: ACTH (1-13) is a peptide fragment of adrenocorticotropic hormone (ACTH; Item No. 24257), a peptide hormone found in the brain that is involved in the biological stress response.{45140} An acetylated form of ACTH (1-13), α-melanocyte stimulating hormone (α-MSH), is formed in the intermediate lobe of the pituitary gland by cleavage of ACTH (1-39), as well as in keratinocytes, astrocytes, monocytes, and gastrointestinal cells.{45140,47500} ACTH (1-13) is an agonist of melanocortin receptor 3 (MC3R) and MC4R, inducing cAMP production in vitro with EC50 values of 0.18 and 19 nM, respectively, which is similar in potency to that of α-MSH.{45139} It induces differentiation of melanocytes when used at concentrations ranging from 0.001 to 1,000 nM.{48426} ACTH (1-13) (40 and 400 pmol, i.c.v.) decreases food intake in broiler chicks.{47501}

• Artikelnummer: CAY27150-1
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 27150-1
• Green Labware: Nein
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK