Formulation: A solution in water
Formal Name: adenosine 5′-(trihydrogen diphosphate), monoanhydride with phosphorothioic acid, tetrasodium salt
Purity: ≥95%
Formula Markup: C10H12N5O12P3S • 4Na
Formula Weight: 611,2
Shelf life (days): 730
CAS Number: 88453-52-5
Notes: Adenosine-5'-O-(3-thiotriphosphate) (ATPγS) is an agonist of the purinergic P2Y11 receptor.{65762} It induces inositol phosphate accumulation in CHO-K1 cells expressing the human or canine P2Y11 receptor (EC50s = 1.2 and 19.3 µM, respectively). ATPγS (10 µM) inhibits Junin virus-induced increases in mRNA encoding bone morphogenetic protein 6 (BMP6) and reduces particle forming units (PFUs) in Junin virus-infected primary rat osteoblasts.{65763} It induces insulin secretion by MIN6 pancreatic β-cells when used at a concentration of 25 µM.{65764}