Formal Name: N-[9-(5-O-phosphono-β-D-ribofuranosyl)-9H-purin-6-yl]-L-aspartic acid, tetraammonium salt
Purity: ≥95%
Formula Markup: C14H14N5O11P • 4NH4
Formula Weight: 531,4
Shelf life (days): 730
Notes: Adenylosuccinic acid is a purine nucleotide and an intermediate in the purine nucleotide cycle.{52338} It is converted into AMP and fumarate by adenylosuccinate lyase in the cytosol. Adenylosuccinic acid (10 µM) inhibits calcium-induced activation of non-selective cation channels in isolated rat brown adipocytes in a patch-clamp assay.{52339} Adenylosuccinic acid (10 µM) increases glucose-induced insulin exocytosis in 832/13 INS-1 pancreatic β-cells.{52340} It induces contractions in isolated guinea pig uterus strips when used at a concentration of 100 µM.{52341}