AGN 193109-d7, CAS 1216429-25-2

Formulation: A solid

Formal Name: 4-[2-[5,6-dihydro-5,5-dimethyl-8-(4-methylphenyl-d7)-2-naphthalenyl]ethynyl]-benzoic acid

Purity: ≥99% deuterated forms (d1-d7).

Formula Markup: C28H17D7O2

Formula Weight: 399,5

Shelf life (days): 1460

CAS Number: 1216429-25-2

Notes: AGN 193109-d7 is intended for use as an internal standard for the quantification of AGN 193109 (Item No. 23975) by GC- or LC-MS. AGN 193109 is an antagonist of retinoic acid receptors (RARs).{41300} AGN 193109 decreases expression of cytokeratin K5-8, 13, 14, 16, 17, and 19 genes, markers of retinoid action in ECE16-1 cells, when co-administered with TTNPB (Item No. 16144) but not when used alone. In vivo, AGN 193109 induces cleft palate or frontonasal dysplasia and eye malformations in fetuses of pregnant mice following a single oral dose of 1 mg/kg.{41301}   

• Artikelnummer: CAY23976
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 23976-1
• Green Labware: Nein
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK
• Methode: GC-MS, LC-MS, Isotopenmarkierung