Alizapride-13C-d3 (hydrochloride), CAS 2928067-18-7

Formulation: A solid

Formal Name: 6-methoxy-13C-d3-N-[[1-(2-propen-1-yl)-2-pyrrolidinyl]methyl]-1H-benzotriazole-5-carboxamide, monohydrochloride

Purity: ≥99% deuterated forms (d1-d3)

Formula Markup: C15[13C]H18D3N5O2 • HCl

Formula Weight: 355,9

Shelf life (days): 1460

CAS Number: 2928067-18-7

Notes: Alizapride-13C-d3 is intended for use as an internal standard for the quantification of alizapride (Item No. 25645) by GC- or LC-MS. Alizapride is a dopamine D2 receptor antagonist (Ki = 66-340 nM in radioligand binding assays).{45087} It is selective for dopamine D2 over α1-, α2-, and β-adrenergic receptors (IC50s = >10 µM for all). It reduces decreases in gastrointestinal transit induced by dopamine (Item No. 21992), apomorphine, or bromocriptine (Item No. 14598) in rats when administered at a dose of 5 mg/kg.{60588} Formulations containing alizapride have been used in the treatment of pre- and postoperative nausea.

• Artikelnummer: CAY33471-1
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 33471-1
• Green Labware: Nein
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK
• Methode: GC-MS, LC-MS, Isotopenmarkierung