AM0902, CAS 1883711-97-4

Formulation: A solid

Formal Name: 1-[[3-[2-(4-chlorophenyl)ethyl]-1,2,4-oxadiazol-5-yl]methyl]-1,7-dihydro-7-methyl-6H-purin-6-one

Purity: ≥98%

Formula Markup: C17H15ClN6O2

Formula Weight: 370,8

Shelf life (days): 1460

CAS Number: 1883711-97-4

Notes: AM0902 is a transient receptor potential ankyrin 1 (TRPA1) antagonist (IC50 = 0.131 µM for the human receptor in a calcium mobilization assay).{62973} It is selective for human TRPA1 over human transient receptor potential vanilloid 1 (TRPV1) and TRPV4, rat TRPV1, TRPV3, and transient receptor potential melastatin 8 (TRPM8), and a panel of 40 additional targets at 10 µM. In vivo, AM0902 (10 and 30 mg/kg) reduces the number of tail flinches induced by the TRPA1 agonist allyl isothiocyanate (AITC) in rats.

• Artikelnummer: CAY37290-10
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 37290-10
• Green Labware: Nein
• Verpackungseinheit: 10 mg
• Mengeneinheit: STK
• Methode: Reinstoffe