Angiotensin III (human, mouse), CAS 13602-53-4

Formulation: A crystalline solid

Formal Name: 5-L-isoleucine-2-8-angiotensin II

Purity: ≥98%

Formula Markup: C46H66N12O9

Formula Weight: 931,1

Shelf life (days): 1460

CAS Number: 13602-53-4

Notes: Angiotensin III (Ang III) is a heptapeptide agonist at the angiotensin 1 (AT1) and AT2 receptors, with a 30-fold higher affinity for AT2 compared with AT1 in HEK293 cells.{26232,34120} Ang III is the preferred agonist for renal AT2 receptors, which are responsible for sodium excretion into the urine.{34101} Ang III induces the same level of aldosterone synthesis as Ang II but has lower vasoconstrictive activity in vivo.{34099} In the brain renin-angiotensin system, Ang III increases sympathetic nerve activity and vasopressin release and dampens the baroreflex leading to higher blood pressure.{34100}

• Artikelnummer: CAY21618-5
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 21618-5
• Green Labware: Nein
• Verpackungseinheit: 5 mg
• Mengeneinheit: STK