Arginine Vasotocin (trifluoroacetate salt)

Formulation: A lyophilized powder

Formal Name: 8-L-arginine-oxytocin, trifluoroacetate salt

Purity: ≥95%

Formula Markup: C43H67N15O12S2 • XCF3COOH

Formula Weight: 1050,2

Shelf life (days): 1460

Notes: Arginine vasotocin is a nonapeptide hormone agonist of the AVT receptor (EC50 = 13 nM for eliciting membrane currents in X. laevis oocytes).{36550} Arginine vasotocin is synthesized in the pineal recess and subcommissural organ by ependymal cells and released into the cerebrospinal fluid.{36555} It inhibits the induction of sleep and release of hypothalamic releasing and inhibiting hormones. Arginine vasotocin stimulates glycogen phosphorylase α activity and incorporation of phosphate into phosphatidylinositol in rat hepatocytes (EC50s = 0.5 nM and 6.3 nM, respectively).{36551} Following a two-minute pulse of arginine vasotocin (1 μM) to neurons isolated from rat suprachiasmatic nuclei, 40.6% of neurons show an increase in firing rate with 11% of the activated neurons responding only to arginine vasotocin and not argipressin (Item No. 24154).{36553} Arginine vasotocin (0.1 μg, i.c.v.) activates sexual behavior in male newts and increases the number of clasps per male from saline control levels of 0.6 to 2.9 in an eight-hour period.{36552} In rainbow trout, arginine vasotocin (0.1 ng/g, i.c.v.) reduces food intake by over 95% and, after eight hours, increases cortisol and glucose levels by 89% and 27%, respectively.{36554}

• Artikelnummer: CAY24768
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 24768-5
• Green Labware: Nein
• Verpackungseinheit: 5 mg
• Mengeneinheit: STK