Formulation: A solid
Formal Name: α-amino-5-(1,1-dimethylethyl)-2,3-dihydro-3-oxo-4-isoxazolepropanoic acid, hydrate
Purity: ≥98%
Formula Markup: C10H16N2O4 • XH2O
Formula Weight: 228,2
Shelf life (days): 1460
Notes: ATPA is an agonist of ionotropic glutamate receptor 5 (GluR5/GluK1; Ki = 0.0043 µM).{57120} It is selective for GluR5 over GluR1-4 (Kis = 6-14 µM), as well as GluR6 (Ki = >1,000 µM). ATPA induces inward currents in HEK293 cells expressing recombinant human GluR5 and isolated rat dorsal root ganglion (DRG) neurons (EC50s = 2.1 and 0.6 µM, respectively).