AZD 4635, CAS 1321514-06-0

Formulation: A crystalline solid

Formal Name: 6-(2-chloro-6-methyl-4-pyridinyl)-5-(4-fluorophenyl)-1,2,4-triazin-3-amine

Purity: ≥98%

Formula Markup: C15H11ClFN5

Formula Weight: 315,7

Shelf life (days): 1460

CAS Number: 1321514-06-0

Notes: AZD 4635 is an adenosine A2 receptor antagonist (Ki = 1.7 nM for the human receptor).{47334} It inhibits adenosine-induced cAMP production in CHO cells expressing the human A2 receptor (IC50 = 0.79 μM) and reverses suppression of IFN-γ secretion induced by 5'-N-ethylcarboxamidoadenosine (NECA; Item No. 21420) in CD8+ T cells. AZD 4635 reduces tumor growth when administered alone and in combination with checkpoint inhibitors in syngeneic mouse tumor models.

• Artikelnummer: CAY26322-5
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 26322-5
• Green Labware: Nein
• Verpackungseinheit: 5 mg
• Mengeneinheit: STK