Formulation: A solution in ethanol
Formal Name: 1-O-hexadecyl-2-O-(9-carboxyoctanoyl)-sn-glyceryl-3-phosphocholine
Purity: ≥98%
Formula Markup: C33H66NO9P
Formula Weight: 651,9
Shelf life (days): 365
CAS Number: 354583-69-0
Notes: Oxidized low-density lipoprotein (oxLDL) particles contain low molecular weight species which promote the differentiation of monocytes via the nuclear receptor PPARγ.{8499} One of these substances was recently isolated and purified from oxLDL, and identified as azelaoyl PAF.{8953} Azelaoyl PAF is a potent PPARγ agonist which competes for the thiazolidinedione binding site. Azelaoyl PAF is more potent than 15-deoxy-Δ12,14-prostaglandin J2, and equipotent with rosiglitazone as a ligand for this receptor.{8953}