β-Endorphin (human) (trifluoroacetate salt)

Formulation: A lyophilized powder

Formal Name: L-tyrosylglycylglycyl-L-phenylalanyl-L-methionyl-L-threonyl-L-seryl-L-a-glutamyl-L-lysyl-L-seryl-L-glutaminyl-L-threonyl-L-prolyl-L-leucyl-L-valyl-L-threonyl-L-leucyl-L-phenylalanyl-L-lysyl-L-asparaginyl-L-alanyl-L-isoleucyl-Lisoleucyl-L-lysyl-L-asparaginyl-L-alanyl-L-tyrosyl-L-lysyl-L-lysylglycyl-L-glutamic acid, trifluoroacetate salt

Purity: ≥95%

Formula Markup: C158H251N39O46S • XCF3COOH

Formula Weight: 3465

Shelf life (days): 1460

Notes: β-Endorphin is an endogenous 31-amino acid neuropeptide and opioid receptor agonist that binds to μ-, δ-, and κ-opioid receptors (Kis = 3.73, 5.02, and 32.7 nM, respectively, in COS-1 cells expressing rat receptors).{41636} It binds to rat and mouse brain membrane preparations (IC50s = 0.33 and 0.67 nM, respectively) and induces chemotaxis of human monocytes in vitro when used at a concentration of 0.1 pM.{41637,40895,40896} Intracerebroventricular administration of β-endorphin increases the latency to tail withdrawal in response to thermal stimuli in mice with a median antinociceptive dose (AD50) value of 27 pmol per animal.{41637} It also increases preference for the drug-paired place in a conditioned place preference test when administered to rats intracerebroventricularly at a dose of 5 μg.{41638}

• Artikelnummer: CAY24955-1
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 24955-1
• Green Labware: Nein
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK