Balaglitazone, CAS 199113-98-9

Formulation: A crystalline solid

Formal Name: 5-[[4-[(3,4-dihydro-3-methyl-4-oxo-2-quinazolinyl)methoxy]phenyl]methyl]-2,4-thiazolidinedione

Purity: ≥98%

Formula Markup: C20H17N3O4S

Formula Weight: 395,4

Shelf life (days): 1460

CAS Number: 199113-98-9

Notes: Balaglitazone is a partial agonist of peroxisome proliferator-activated receptor γ (PPARγ; EC50 = 1.351 μM in a transactivation assay).{48619} It decreases non-fasting plasma glucose levels in diabetic db/db mice (ED90 = 3 mg/kg per day). Balaglitazone (5 and 10 mg/kg per day) decreases plasma levels of insulin and glucose in an oral glucose tolerance test in diet-induced obese rats.{48620} In doxorubicin-resistant K562 human myelogenous leukemia cells, balaglitazone (25 μM) decreases P-glycoprotein (P-gp) levels, increases intracellular accumulation of the P-gp substrate rhodamine 123 (Item No. 16672), and sensitizes cells to doxorubicin (Item No. 15007).{48621}

• Artikelnummer: CAY28866-25
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 28866-25
• Green Labware: Nein
• Verpackungseinheit: 25 mg
• Mengeneinheit: STK