BAY u9773, CAS 154978-38-8

Formulation: A solution in ethanol

Formal Name: 4-[[(1R,2E,4E,6Z,9Z)-1-[(1S)-4-carboxy-1-hydroxybutyl]-2,4,6,9-pentadecatetraenyl]thio]-benzoic acid

Purity: ≥95%

Formula Markup: C27H36O5S

Formula Weight: 472,6

Shelf life (days): 365

CAS Number: 154978-38-8

Notes: BAY u9773 is a cysteinyl leukotriene 1 (CysLT1) and CysLT2 receptor antagonist.{12765} It inhibits contractions induced by leukotriene D4 (LTD4; Item No. 20310) or LTC4 (Item No. 20210) in isolated guinea pig trachea, rat lung, ferret spleen, and sheep bronchus (pA2s = 6.8-7.4). BAY u9773 (0.1 mg/kg) suppresses airway hypersensitivity and bronchoalveolar lavage fluid (BALF) eosinophil infiltration in a guinea pig model of ovalbumin-induced asthma.{68315} It also increases the latency to generalized seizures and decreases the EEG amplitude in a mouse model of seizures induced by pentylenetetrazol (PTZ; Item No. 18682).{68316}

• Artikelnummer: CAY70770-25
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 70770-25
• Green Labware: Nein
• Verpackungseinheit: 25 µg
• Mengeneinheit: STK