Benidipine (hydrochloride), CAS 91599-74-5

Formulation: A crystalline solid

Formal Name: (4R)-rel-1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid, 3-methyl 5-[(3R)-1-(phenylmethyl)-3-piperidinyl] ester, monohydrochloride

Purity: ≥98%

Formula Markup: C28H31N3O6 • HCl

Formula Weight: 542

Shelf life (days): 1460

CAS Number: 91599-74-5

Notes: Benidipine is an orally bioavailable blocker of L-, T-, and N-type calcium channels.{34214} In guinea pig ventricular cells benidipine has an IC50 of 2.7 nM for calcium currents, determined using whole cell voltage clamp electrophysiology.{34216} It prevents oxidative stress dose-dependently in vitro, decreases blood pressure in spontaneously hypertensive rats (at 3 and 10 mg/kg), and is neuroprotective for neural stem cells after oxidative stress-induced injury.{34213,34215,34211} Benidipine is also a competitive antagonist at mineralocorticoid receptors.{34214}

• Artikelnummer: CAY21607-50
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 21607-50
• Green Labware: Nein
• Verpackungseinheit: 50 mg
• Mengeneinheit: STK