Formulation: A solid
Formal Name: N-(methyl-d3)-2-pyridineethanamine, dihydrochloride
Purity: ≥99% deuterated forms (d1-d3)
Formula Markup: C8H9D3N2 • 2HCl
Formula Weight: 212,1
Shelf life (days): 1460
CAS Number: 244094-72-2
Notes: Betahistine-d3 is intended for use as an internal standard for the quantification of betahistine (Item No. 27602) by GC- or LC-MS. Betahistine is a histamine H3 receptor antagonist and histamine H1 receptor agonist.{45328} In vivo, betahistine dilates pre-capillary arterioles and increases blood flow to the stria vascularis in guinea pigs.{45329,45330} Betahistine (8 mg/kg) reduces weight gain and increased feeding behavior induced by olanzapine (Item No. 11937) in female rats.{45331} Formulations containing betahistine have been used in the treatment of balance disorders and vertigo symptoms associated with Meniere's disease.