Bezafibrate-d4, CAS 1189452-53-6

Formulation: A solid

Formal Name: 2-[4-[2-[(4-chlorobenzoyl-2,3,5,6-d4)amino]ethyl]phenoxy]-2-methyl-propanoic acid

Purity: ≥99% deuterated forms (d1-d4)

Formula Markup: C19H16ClD4NO4

Formula Weight: 365,8

Shelf life (days): 1460

CAS Number: 1189452-53-6

Notes: Bezafibrate-d4 is intended for use as an internal standard for the quantification of bezafibrate (Item No. 10009145) by GC- or LC-MS. Bezafibrate is a non-selective agonist of peroxisome proliferator-activated receptors (PPARs; EC50s = 50, 60, and 20 μM for human PPARα, PPARγ, and PPARδ, respectively).{10670} It reduces triglyceride levels and the size of lipid droplets in an oleic acid-induced HepaRG hepatocyte model of steatosis when used at a concentration of 25 μM.{42456} Bezafibrate (10 mg/kg per day) reduces plasma VLDL and LDL mass and triglyceride and free fatty acid levels in a high-fructose plus lard diet-induced rat model of insulin resistance.{42937}

• Artikelnummer: CAY28526
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 28526-1
• Green Labware: Nein
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK
• Methode: GC-MS, LC-MS, Isotopenmarkierung