Bicalutamide-d4, CAS 1185035-71-5

Formulation: A solid

Formal Name: N-[4-cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluorophenyl-2,3,5,6-d4)sulfonyl]-2-hydroxy-2-methyl-propanamide

Purity: ≥99% deuterated forms (d1-d4)

Formula Markup: C18H10D4F4N2O4S

Formula Weight: 434,4

Shelf life (days): 1460

CAS Number: 1185035-71-5

Notes: Bicalutamide-d4 is intended for use as an internal standard for the quantification of bicalutamide (Item No. 14250) by GC- or LC-MS. Bicalutamide is a non-steroidal androgen receptor antagonist that binds the androgen receptor (Ki = 12.5 μM; IC50 = 1.2 μM), preventing its activation and subsequent upregulation of androgen responsive genes by androgenic hormones.{22431,22433} Bicalutamide is frequently used to examine the role of androgen receptor inactivation in the proliferation of prostate cancer cells and has served as a molecular template for the design and structural optimization of more selective androgen receptor modulators for androgen therapy.{22432,22430}

• Artikelnummer: CAY22377-1
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 22377-1
• Green Labware: Nein
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK
• Methode: GC-MS, LC-MS, Isotopenmarkierung