Formulation: A crystalline solid
Formal Name: 3,4,5,6,7,9-hexahydro-3,3,6,6-tetramethyl-9-[4-[(2-methylphenyl)methoxy]phenyl]-1H-xanthene-1,8(2H)-dione
Purity: ≥98%
Formula Markup: C31H34O4
Formula Weight: 470,6
Shelf life (days): 730
CAS Number: 684238-37-7
Notes: BMS 986187 is a positive allosteric modulator of δ-opioid receptors.{38565} In the presence of the endogenous δ-opioid receptor agonist leu-enkephalin, BMS 986187 has an average EC50 value of 30 nM for β-arrestin recruitment, but has little to no activity in the absence of an agonist. It is 100-fold selective for δ- over µ-opioid receptors in the presence of leu-enkephalin and the endogenous µ-opioid receptor agonist endomorphin I, respectively.