Formulation: A crystalline solid
Formal Name: 8-[2-[4-(2-methoxyphenyl)-1-piperazinyl]ethyl]-8-azaspiro[4.5]decane-7,9-dione, dihydrochloride
Purity: ≥98%
Formula Markup: C22H31N3O3 • 2HCl
Formula Weight: 458,4
Shelf life (days): 1460
CAS Number: 21102-95-4
Notes: BMY 7378 is an antagonist of the α2C-adrenoceptor and α1D-adrenoceptor with pKi values of 6.54 and 8.2, respectively, that has been used in functional systems to assess the contribution of these receptors in vascular smooth muscle contraction.{33564,33563} It also acts as a partial agonist at the serotonin 5-HT1A receptor with a pKi value of 8.3.{33564}