Bombesin (trifluoroacetate salt)

Formulation: A lyophilized powder

Formal Name: 5-oxo-L-prolyl-L-glutaminyl-L-arginyl-L-leucylglycyl-L-asparaginyl-L-glutaminyl-L-tryptophyl-L-alanyl-L-valylglycyl-L-histidyl-L-leucyl-L-methioninamide, trifluoroacetate salt

Purity: ≥95%

Formula Markup: C71H110N24O18S • XCF3COOH

Formula Weight: 1619,9

Shelf life (days): 1460

Notes: Bombesin is a neuropeptide with diverse biological activities originally isolated from the skin of B. bombina and B. variegata variegata amphibians.{40598,40599} It binds to the gastrin-releasing peptide receptor (GRPR) in rat pancreatic acinar cells (Ki = 1.88 nM) and to frog bombesin receptor subtype 4 (BB4) in CHO cells overexpressing the receptor (Ki = 1.7 nM).{40600} Hypothalamic paraventricular microinfusion of bombesin (100 ng per animal) increases blood glucose, free fatty acids, and corticosterone levels in rats.{40601} Bombesin (50 ng per animal) injection into the preoptic area decreases food intake by food-deprived or insulin pretreated rats.{40602} It delays gastric emptying in rats by 55.8% when administered at a dose of 16 μg/kg (i.p.) and inhibits gastric secretion at a dose of 500 ng per animal.{40603,40604}

• Artikelnummer: CAY24151-500
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 24151-500
• Green Labware: Nein
• Verpackungseinheit: 500 µg
• Mengeneinheit: STK