Buclizine (hydrochloride), CAS 129-74-8

Formulation: A crystalline solid

Formal Name: 1-[(4-chlorophenyl)phenylmethyl]-4-[[4-(1,1-dimethylethyl)phenyl]methyl]-piperazine, dihydrochloride

Purity: ≥98%

Formula Markup: C28H33ClN2 • 2HCl

Formula Weight: 506

Shelf life (days): 1460

CAS Number: 129-74-8

Notes: Buclizine is an antihistamine.{36933} It reduces bronchoconstriction and lethality induced by aerosolized histamine in guinea pigs when administered at a dose of 1 mg/kg. Buclizine (40-200 mg/kg) induces gross malformations, including fusion of the tongue to the palate, cleft palate, micrognathia, and micromelia, and bone malformations in rats.{36934} It also inhibits cancer cell growth by binding to translationally controlled tumor protein (TCTP) and inducing cell differentiation.{36935} Formulations containing buclizine have been used to treat nausea induced by pregnancy and motion sickness.

• Artikelnummer: CAY25641-1
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 25641-1
• Green Labware: Nein
• Verpackungseinheit: 1 g
• Mengeneinheit: STK