Bufuralol-d9 (hydrochloride), CAS 1173023-51-2

Formulation: A solid

Formal Name: α-[[(1,1-dimethylethyl-d9)amino]methyl]-7-ethyl-2-benzofuranmethanol, monohydrochloride

Purity: ≥99% deuterated forms (d1-d9)

Formula Markup: C16H14D9NO2 • HCl

Formula Weight: 306,9

Shelf life (days): 1460

CAS Number: 1173023-51-2

Notes: Bufuralol-d9 is intended for use as an internal standard for the quantification of bufuralol (Item No. 17794) by GC- or LC-MS. Bufuralol is a non-selective antagonist of β-adrenergic receptors (β-ARs) that also has partial agonist activity.{29042,29043,45566} It decreases mean arterial blood pressure and increases abdominal aortic blood flow in anesthetized cats when administered intravenously at doses of 0.3 and 1 mg/kg.{45566} Bufuralol is hydroxylated at the 1' position by the cytochrome P450 (CYP) isoform CYP2D6 and has been used as a substrate to measure CYP2D6 activity.{37036,29042,11736,45565}

• Artikelnummer: CAY29081
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 29081-1
• Green Labware: Nein
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK
• Methode: GC-MS, LC-MS, Isotopenmarkierung