Buserelin-NHNH2 (trifluoroacetate salt)

Formulation: A lyophilized solid

Formal Name: 6-[O-(1,1-dimethylethyl)-D-serine]-9-(N-ethyl-L-prolinamide)-1-9-luteinizing hormone-releasing factor (swine), hydrazide, 2,2,2-trifluoroacetate

Purity: ≥95%

Formula Markup: C58H83N17O13 • XCF3COOH

Formula Weight: 1226,4

Shelf life (days): 1460

Notes: Buserelin is a synthetic gonadotropin-releasing hormone (GNRH) agonist that is at least 20 times more potent than GNRH.{39408,39411} It is a long-acting agent that, after an initial increase in sex hormone levels, decreases the level of circulating gonadotropins and sex hormones.{39411} Buserelin (20 µg/kg) reduces tumor growth in a DMBA-induced rat model of mammary cancer.{39409} It induces enteric neurodegeneration, decreasing the number of luteinizing hormone receptor-positive neurons in the rat gastrointestinal tract, when administered at a dose of 1 mg/kg for 5 days.{39410} Formulations containing buserelin have been used in the treatment of hormone-dependent prostate cancer and endometriosis.

• Artikelnummer: CAY24156-1
• Hersteller: Cayman Chemical
• Hersteller Artikelnummer: 24156-1
• Green Labware: Nein
• Verpackungseinheit: 1 mg
• Mengeneinheit: STK