Formulation: A crystalline solid
Formal Name: N-(4-butylphenyl)-5-nitro-2-furancarboxamide
Purity: ≥98%
Formula Markup: C15H16N2O4
Formula Weight: 288,3
Shelf life (days): 730
CAS Number: 346691-38-1
Notes: C-170 is an inhibitor of stimulator of interferon genes (STING).{35390,50925} It binds to STING, inhibits its palmitoylation, and prevents the recruitment and phosphorylation of TBK1.{35390} It selectively reduces human and mouse STING-, but not RIG-I- or TBK1-, mediated IFN-β reporter activity in HEK293 cells when used at concentrations ranging from 0.02 to 2 µM.