Formulation: A crystalline solid
Formal Name: N-(4-hexylphenyl)-5-nitro-2-furancarboxamide
Purity: ≥98%
Formula Markup: C17H20N2O4
Formula Weight: 316,4
Shelf life (days): 730
CAS Number: 2244881-69-2
Notes: C-171 is an inhibitor of stimulator of interferon genes (STING).{35390,50925} It binds to STING, inhibits its palmitoylation, and prevents the recruitment and phosphorylation of TBK1.{35390} It selectively reduces human and mouse STING-, but not RIG-I or TBK1-, mediated IFN-β reporter activity in HEK293 cells when used at concentrations ranging from 0.02 to 2 μM.